Phenotypes for Lyz2 Nlrp3 MGI:3850048 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nlrp3^tm2Hhf/Nlrp3⁺ Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	involves: 129/Sv * 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (41 available)
Nlrp3^tm2Hhf mutation (1 available); any Nlrp3 mutation (61 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:150054 )

• mice are either stillborn or day within one day of birth

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
familial cold autoinflammatory syndrome 1		DOID:0090062	OMIM:120100	J:150054

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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