Phenotypes for Lfng Mfng MGI:3849431 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lfng^tm1Rjo/Lfng^tm1Rjo Mfng^tm1Seco/Mfng^tm1Seco
Genetic Background	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfng^tm1Rjo mutation (0 available); any Lfng mutation (32 available)
Mfng^tm1Seco mutation (1 available); any Mfng mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:149312 )

• fewer than expected are found at weaning however survivors are viable and fertile

postnatal lethality, incomplete penetrance ( J:149312 )

• fewer than expected are found at weaning

• reduction in numbers found at weaning is not greater than that of Lfng^tm1Rjo single homozygous littermates

skeleton

abnormal skeleton morphology ( J:149312 )

• skeleton phenotype is not significantly different from that of Lfng^tm1Rjo single homozygous mice

decreased caudal vertebrae number ( J:149312 )

abnormal rib morphology ( J:149312 )

limbs/digits/tail

decreased caudal vertebrae number ( J:149312 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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