Phenotypes Associated with This Genotype

Genotype
MGI:3849175

• Allelic Composition: Atoh1^{tm1(cre/ERT2)Mhos}/Atoh1^{tm1(cre/ERT2)Mhos}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal cochlear VIII nucleus morphology ( J:149533 )

• at E18.5, the cochlear nucleus (CN) is indiscernible

• granule cell number is significantly reduced in CN

• GABAergic inhibitory neurons are maintained in the mutant CN

abnormal glutaminergic neuron morphology ( J:149533 )

• greatly reduced numbers of glutamatergic neurons are detected in the dorsal cochlear nucleus at E18.5