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Phenotypes Associated with This Genotype
Genotype
MGI:3847937
Allelic
Composition		 Tg(MMTV-NFKBIA*S32A*S36A)13Mka/?
Genetic
Background		 involves: C57BL/6
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands
abnormal lactation ( J:90978 )
• lactation defect similar to mice homozygous for Chuktm2Mka resulting in death of all newborns within 48 hours

reproductive system
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands

integument
abnormal mammary gland growth during pregnancy ( J:90978 )
• defective lobuloalveolar development of mammary glands
abnormal lactation ( J:90978 )
• lactation defect similar to mice homozygous for Chuktm2Mka resulting in death of all newborns within 48 hours

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory