Analysis Tools
behavior/neurological
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• consolidation and storage of long-term nondeclarative taste memories is impaired in these mice when given doxycycline prior to or within three weeks of training
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• mice given doxycycline have impairment of conditioned taste aversion
• mice are trained to avoid saccharin-containing water by being given a LiCl injection after water consumption
• control mice choose unsweetened water about 83.58% of the time 30 days after training
• mutant mice given doxycycline prior to training only choose unsweetened water 32.24% of the time
• mutant mice given doxycycline 2 weeks after training choose unsweetened water 25.63% of the time
• mutant mice given doxycycline 3 weeks to 4 weeks after training choose unsweetened water 27.99% of the time
• mutant mice given doxycycline 4 weeks after training choose unsweetened water at the same frequency as controls
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