Tg(Actb-tTA)1Jzt
Transgene Detail

Summary

• Symbol: Tg(Actb-tTA)1Jzt
• Name: transgene insertion 1, Joe Z Tsien
• MGI ID: MGI:3038371
• Synonyms: floxed-stop-tTA, stop-tTA
• Transgene: Tg(Actb-tTA)1Jzt Location: unknown
• Alliance: Tg(Actb-tTA)1Jzt page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: These transgenic mice express the tetracycline-inhibitable transcription factor (tTA) under the control of beta actin promoter. There is a floxed translational stop codon between the promoter and the tTA coding sequence. The tTA protein is only produced in cells where cre recombinase was expressed. (J:77659)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77659 Shimizu E, et al., NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science. 2000 Nov 10;290(5494):1170-4
• All: 5 reference(s)