Phenotypes Associated with This Genotype

Genotype
MGI:3845664

• Allelic Composition: Vcam1^tm2Flv/Vcam1^tm2Flv; Tg(Mx1-cre)1Cgn/0
• Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal blood cell morphology/development ( J:123142 )

• after pIpC injection, the number of colony forming unit cultures in the peripheral blood is significantly but variably increased compared to controls

• the degree of increase in colony forming unit cultures correlates to the extent of recombination in bone marrow nonhematopoietic cells

decreased bone marrow cell number ( J:123142 )

• after pIpC injection, progenitor cell numbers and total cell numbers are decreased compared to controls