Phenotypes Associated with This Genotype

Genotype
MGI:3844692

• Allelic Composition: a/a; Oca2^p/Oca2^p
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

pigmentation

decreased ear pigmentation ( J:78801 , J:36414 )

• the ears appear much lighter than ears of normal mice (J:78801)

abnormal coat/hair pigmentation ( J:78801 , J:12958 )

abnormal hair follicle melanocyte morphology ( J:78801 )

• black and brown pigmentation in hair is significantly reduced

abnormal hair follicle melanin granule morphology ( J:12958 )

• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps

• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag

abnormal hair follicle melanin granule distribution ( J:12958 )

• pigment occurs in loose clumps

abnormal hair follicle melanin granule shape ( J:12958 )

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

decreased skin pigmentation ( J:36414 )

decreased eye pigmentation ( J:78801 )

• eyes are similar in color to eyes of albino mice

vision/eye

decreased eye pigmentation ( J:78801 )

• eyes are similar in color to eyes of albino mice

craniofacial

decreased ear pigmentation ( J:78801 , J:36414 )

• the ears appear much lighter than ears of normal mice (J:78801)

hearing/vestibular/ear

decreased ear pigmentation ( J:78801 , J:36414 )

• the ears appear much lighter than ears of normal mice (J:78801)

integument

decreased ear pigmentation ( J:78801 , J:36414 )

• the ears appear much lighter than ears of normal mice (J:78801)

abnormal coat/hair pigmentation ( J:78801 , J:12958 )

abnormal hair follicle melanocyte morphology ( J:78801 )

• black and brown pigmentation in hair is significantly reduced

abnormal hair follicle melanin granule morphology ( J:12958 )

• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps

• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag

abnormal hair follicle melanin granule distribution ( J:12958 )

• pigment occurs in loose clumps

abnormal hair follicle melanin granule shape ( J:12958 )

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

decreased skin pigmentation ( J:36414 )

growth/size/body

decreased ear pigmentation ( J:78801 , J:36414 )

• the ears appear much lighter than ears of normal mice (J:78801)