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Phenotypes Associated with This Genotype
Genotype
MGI:3844018
Allelic
Composition		 Map3k6tm1Hijo/Map3k6+
Genetic
Background		 B6.129P2-Map3k6tm1Hijo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k6tm1Hijo mutation (3 available); any Map3k6 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased incidence of tumors by chemical induction ( J:148044 )
• increased incidence of papillomas in a 2-stage skin tumorigenesis model using DMBA and TPA compared to wild-type controls but decreased compared to homozygous mutant mice

neoplasm
increased incidence of tumors by chemical induction ( J:148044 )
• increased incidence of papillomas in a 2-stage skin tumorigenesis model using DMBA and TPA compared to wild-type controls but decreased compared to homozygous mutant mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory