Phenotypes for Cdkn1b Rbx1 MGI:3842439 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cdkn1b^tm1Mlf/Cdkn1b^tm1Mlf Rbx1^Gt(XB674)Byg/Rbx1^Gt(XB674)Byg
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1b^tm1Mlf mutation (2 available); any Cdkn1b mutation (26 available)
Rbx1^Gt(XB674)Byg mutation (0 available); any Rbx1 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:147759 )

• die between E9.5 and E10.5

cellular

cellular phenotype ( J:147759 )

N	• unlike in Rbx1^Gt(XB674)Byg single homozygous mice, double homozygous embryos show normal cell proliferation at E6.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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