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Phenotypes Associated with This Genotype
Genotype
MGI:3841457
Allelic
Composition		 Ksr1tm1Shaw/Ksr1tm1Shaw
Tg(MMTV-PyVT)634Mul/?
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ksr1tm1Shaw mutation (0 available); any Ksr1 mutation (48 available)
Tg(MMTV-PyVT)634Mul mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor latency ( J:75739 )
• onset of tumor formation is delayed with no mammary tumors detected until 65 +/- 9 days of age compared to 35 +/- 8 days of age for heterozygous controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory