Phenotypes Associated with This Genotype

Genotype
MGI:3841028

• Allelic Composition: Pax2^1Neu/Pax2⁺
• Genetic Background: involves: 102 * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina vasculature morphology ( J:37055 )

abnormal optic disk morphology ( J:37055 )

• the optic disk is abnormally broad and cup-shaped compared to in wild-type mice

abnormal retina layer morphology ( J:37055 )

• inner retinal layers are thinner than normal

abnormal retina neuronal layer morphology ( J:37055 )

• all neural layers are thinner than in wild-type mice

decreased retina ganglion cell number ( J:37055 )

thin retina ganglion layer ( J:37055 )

abnormal retina nerve fiber layer morphology ( J:37055 )

• thin

renal/urinary system

kidney cyst ( J:37055 )

• in some mice

small kidney ( J:37055 )

• in some mice

single kidney ( J:37055 )

• in 3 in 50 mice

nervous system

decreased retina ganglion cell number ( J:37055 )

abnormal optic disk morphology ( J:37055 )

• the optic disk is abnormally broad and cup-shaped compared to in wild-type mice

cardiovascular system

abnormal retina vasculature morphology ( J:37055 )

growth/size/body

kidney cyst ( J:37055 )

• in some mice