Phenotypes for En1 Gt(ROSA)26Sor MGI:3839921 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	En1^tm2(cre)Gld/En1⁺ Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1^tm2(cre)Gld mutation (0 available); any En1 mutation (34 available)
Gt(ROSA)26Sor^tm1(DTA)Riet mutation (0 available); any Gt(ROSA)26Sor mutation (1084 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal ventral interneuron 1 morphology ( J:106437 )

• decrease in the number of V1 neurons in the spinal cord

abnormal CNS synaptic transmission ( J:106437 )

• significant increase in the length of both step cycle period and motor neuron burst duration during fictive locomotion

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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