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Phenotypes Associated with This Genotype
Genotype
MGI:3839918
Allelic
Composition
Sim1tm1.1(cre)Gld/Sim1+
Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld/0
Genetic
Background
involves: 129S1/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sim1tm1.1(cre)Gld mutation (0 available); any Sim1 mutation (52 available)
Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• marked decrease in the rhythmicity of spinal cord locomotor like outputs and increase in the variance of flexor related bursts between the left and right halves in the presence of allatostatin

behavior/neurological
• after application of allatostatin to the L2 - L4 segments 5 of 8 mice showed profound changes in their gate with changes in the timing and duration of both the stance and swing phases of the gait
• however, in the absence of treatment no gait abnormalities were seen


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory