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Phenotypes Associated with This Genotype
Genotype
MGI:3837415
Allelic
Composition
Lrp5tm1Kry/Lrp5tm1Kry
Tph1tm1Kry/Tph1+
Tg(Vil1-cre)20Syr/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5tm1Kry mutation (0 available); any Lrp5 mutation (81 available)
Tg(Vil1-cre)20Syr mutation (3 available)
Tph1tm1Kry mutation (0 available); any Tph1 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
N
• loss of expression of 1 copy of Tph1 in the gut rescues the bone phenotype seen in Lrp5 null mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory