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Phenotypes Associated with This Genotype
Genotype
MGI:3837408
Allelic
Composition
Tph1tm1Kry/Tph1tm1Kry
Tg(Col1a1-cre)1Kry/0
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Col1a1-cre)1Kry mutation (2 available)
Tph1tm1Kry mutation (0 available); any Tph1 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• unlike mice with conditional deletion in the gut, mice with conditional expression in osteoblasts have normal circulating serotonin levels

skeleton
N
• unlike mice with conditional deletion in the gut, mice with conditional expression in osteoblasts have no significant increase in bone mass or osteoblast proliferation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory