Analysis Tools
immune system
|
• less sensitive to anti-IgM induced proliferation compared to wild-type controls
|
|
• the percentage of peritoneal B220+CD5+ cells is decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
• however, the frequency and number of splenic B cells are similar to wild-type controls
|
|
• basal serum IgG3 levels are decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
|
|
• serum levels of IgM following TNP-Ficoll treatment are reduced compared to wild-type controls
• basal serum IgM levels are decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
|
hematopoietic system
|
• less sensitive to anti-IgM induced proliferation compared to wild-type controls
|
|
• the percentage of peritoneal B220+CD5+ cells is decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
• however, the frequency and number of splenic B cells are similar to wild-type controls
|
|
• basal serum IgG3 levels are decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
|
|
• serum levels of IgM following TNP-Ficoll treatment are reduced compared to wild-type controls
• basal serum IgM levels are decreased compared to wild-type controls but increased compared to mutant mice not carrying the transgene
|
cellular
|
• less sensitive to anti-IgM induced proliferation compared to wild-type controls
|
