cardiovascular system
• mice are almost entirely free of fatty lesions in the aortic root compared to the 75% of atherosclerotic lesions in mice homozygote null for just the Apoe gene
|
homeostasis/metabolism
• total cholesterol levels are extremely high with a mean of 1056 mg/dl compared to 112 mg/dl for controls or 379 mg/dl mice for Apoe null mice
|