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Phenotypes Associated with This Genotype
Genotype
MGI:3832678
Allelic
Composition
Hprt1tm2(AGT)Asku/Y
Tg(REN)64071Sig/?
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm2(AGT)Asku mutation (0 available); any Hprt1 mutation (1272 available)
Tg(REN)64071Sig mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• plasma levels of angiotensin II are increased 40% over non-transgenic controls
• liver levels of angiotensinogen are lower than mice of the AA haplotype
• kidney levels of angiotensinogen are lower than mice of the AA haplotype
• plasma levels are less than in mice of the AG haplotype

cardiovascular system
• blood pressure in males measured at 3 months of age is 117mm Hg compared to 111mm Hg in non-transgenic controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory