Phenotypes Associated with This Genotype

Genotype
MGI:3832436

• Allelic Composition: Itgb6^tm1Des/Itgb6^tm1Des; Tg(SFTPC-ITGB6)1Des/?
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

respiratory system phenotype ( J:51592 )

N • bronchoalveolar lavage abnormalities are largely corrected

respiratory system inflammation ( J:51592 )

• accumulation of lymphocytes around conducting airways and adjacent veins found in 6 of 14 mice examined

• less frequent than in mice only homozygous for Itgb6^tm1Des

immune system

respiratory system inflammation ( J:51592 )

• accumulation of lymphocytes around conducting airways and adjacent veins found in 6 of 14 mice examined

• less frequent than in mice only homozygous for Itgb6^tm1Des

integument

alopecia ( J:51592 )

• inflammatory baldness observed