Phenotypes Associated with This Genotype

Genotype
MGI:3832340

• Allelic Composition: Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt; Tg(CAG-Bgeo,-Fgf4)1Mrt/?; Tg(Msx2-cre)5Rem/?
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:104411 )

N • reversal of abnormalities resulting from loss of Fgf8 alone

N • deltoid tuberosity is normal

polysyndactyly ( J:104411 )

• phenotype due to conditional over expression of Fgf4 retained

fused tarsal bones ( J:104411 )

abnormal limb development ( J:104411 )

abnormal limb bud morphology ( J:104411 )

abnormal digit development ( J:104411 )

growth/size/body

postnatal growth retardation ( J:104411 )

vision/eye

abnormal eyelid morphology ( J:104411 )

reproductive system

abnormal reproductive system morphology ( J:104411 )

embryo

abnormal limb bud morphology ( J:104411 )

skeleton

fused tarsal bones ( J:104411 )