About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3831434
Allelic
Composition		 Gt(ROSA)26Sortm4(Wnt7a)Amc/?
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm4(Wnt7a)Amc mutation (0 available); any Gt(ROSA)26Sor mutation (1061 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal vascular endothelial cell morphology ( J:142352 )
• ectopic expression of Wnt7a in the vascular endothelium outside the CNS of E12.5 embryos leads to expression of GLUT-1, a marker normally associated with the blood-brain barrier

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory