Analysis Tools
immune system
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• in mice in which cre expression is induced, there is a 94% survival rate in irradiated mutant mice receiving wild-type BALB/c bone marrow compared to controls that only had a 57% survival rate
• these mice also have higher weights and have fewer manifestations of GVHD including better skin texture, less fur loss, and more activity
• donor bone marrow engraftment occurred in the mutant mice suggesting the allogenic immune cells present in the mice were being suppressed
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