Analysis Tools
cardiovascular system
|
• the direction of looping is reversed in about half of the embryos at E8.5 - E9.5
|
embryo
| N |
• unlike in mice heterozygous for Nodal tm1Mku and Nodal tm1.1Mku, no midline or anterior/head morphological defects are detected
|
|
• expression analysis indicates complete loss of asymmetric signals in the lateral plate mesoderm
|
growth/size/body
|
• by E13.5
|
hematopoietic system
small spleen
(
J:142430
)
|
• small or absent
|
|
• small or absent
|
immune system
small spleen
(
J:142430
)
|
• small or absent
|
|
• small or absent
|
respiratory system
|
• by E13.5
|
