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Phenotypes Associated with This Genotype
Genotype
MGI:3829017
Allelic
Composition
Ctcftm2Gal/Ctcf+
Tg(Lck-cre)1Cwi/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctcftm2Gal mutation (0 available); any Ctcf mutation (78 available)
Tg(Lck-cre)1Cwi mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• modestly
• the numbers of mature CD4+ and CD8+ cells in the spleen and lymph nodes are reduced compared to in wild-type mice
• however, the ratio of mature single positive cells to double positive cells is normal
• the numbers of mature CD4+ and CD8+ cells in the spleen and lymph nodes are reduced compared to in wild-type mice
• however, the ratio of mature single positive cells to double positive cells is normal

hematopoietic system
• modestly
• the numbers of mature CD4+ and CD8+ cells in the spleen and lymph nodes are reduced compared to in wild-type mice
• however, the ratio of mature single positive cells to double positive cells is normal
• the numbers of mature CD4+ and CD8+ cells in the spleen and lymph nodes are reduced compared to in wild-type mice
• however, the ratio of mature single positive cells to double positive cells is normal

endocrine/exocrine glands
• modestly


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory