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Phenotypes Associated with This Genotype
Genotype
MGI:3822767
Allelic
Composition		 Gt(ROSA)26Sortm1(Hesx1)Jpmb/Gt(ROSA)26Sor+
Tmem163Tg(ACTB-cre)2Mrt/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Hesx1)Jpmb mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tmem163Tg(ACTB-cre)2Mrt mutation (3 available); any Tmem163 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
exencephaly ( J:135132 )
• 10% of embryos exhibit exencephaly
• Background Sensitivity: phenotype is background-dependent, as mutants on C57BL/6J;CD-1 background do not display exencephaly

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory