Phenotypes Associated with This Genotype

Genotype
MGI:3820654

• Allelic Composition: Rag2^tm1Fwa/Rag2^tm1Fwa; Tg(EmuSR-tTa)83Bop/0; Tg(tetO-Nfatct1*)1Grc/0
• Genetic Background: involves: 129S/SvEv * C57BL/6J * CBA/J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal double-positive T cell morphology ( J:141917 )

• 4 to 30% DP thymocytes appear allowing some DN cells to progress to the DP state, which is fewer than in wild-type mice but more than in Rag2 null mice

immune system

abnormal double-positive T cell morphology ( J:141917 )

• 4 to 30% DP thymocytes appear allowing some DN cells to progress to the DP state, which is fewer than in wild-type mice but more than in Rag2 null mice