Phenotypes Associated with This Genotype

Genotype
MGI:3820082

• Allelic Composition: Igf2r^tm2Wag/Igf2r⁺; Del(17)T^hp/+
• Genetic Background: involves: 129/Sv * 129P2/OlaHsd * AKR/J * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:68721 )

• when is Igf2r^tm2Wag inherited paternally and T^hp is maternally, some mice survive birth and reach maturity despite some prenatal lethality

prenatal lethality, incomplete penetrance ( J:68721 )

• when the allele is inherited paternally, fewer than expected mice are born

• however, unlike when only T^hp is inherited maternally, some mice are recovered at birth

limbs/digits/tail

abnormal tail morphology ( J:68721 )

• when is Igf2r^tm2Wag inherited paternally and T^hp is maternally, mice have a bent tail compared to wild-type mice

reproductive system

reproductive system phenotype ( J:68721 )

N • when the allele is inherited paternally, mice are fertile