Analysis Tools
reproductive system
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• oocytes fail to develop in the atrophied ovaries of these mice
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• there is extensive apoptosis of male germ cells in 20-day old males
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• no follicles are observed in the ovaries of 90-day old mice
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small ovary
(
J:141249
)
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• ovaries of adult female mice are only half the size of controls
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• round spermatids are absent in the testis of 20-day old males
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• spermatocyte numbers are depleted in the testes of 3-month old mice
• there is an increase in the number of apoptotic spermatocytes in the testes of 10-day old mice
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• a greater number of spermatocytes reach the pachytene stage of meiosis than controls
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• the seminiferous tubules are much smaller in 3-month old males
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small testis
(
J:141249
)
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• testis are 20-30% smaller than controls at twenty days of age
• testis of adult males are only half the size of controls
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infertility
(
J:141249
)
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• both male and female mice are sterile
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endocrine/exocrine glands
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• no follicles are observed in the ovaries of 90-day old mice
|
small ovary
(
J:141249
)
|
|
• ovaries of adult female mice are only half the size of controls
|
|
|
• the seminiferous tubules are much smaller in 3-month old males
|
small testis
(
J:141249
)
|
|
• testis are 20-30% smaller than controls at twenty days of age
• testis of adult males are only half the size of controls
|
cellular
|
|
• oocytes fail to develop in the atrophied ovaries of these mice
|
|
|
• round spermatids are absent in the testis of 20-day old males
|
|
|
• spermatocyte numbers are depleted in the testes of 3-month old mice
• there is an increase in the number of apoptotic spermatocytes in the testes of 10-day old mice
|
|
|
• a greater number of spermatocytes reach the pachytene stage of meiosis than controls
|
|
|
• there is extensive apoptosis of male germ cells in 20-day old males
|
