Phenotypes Associated with This Genotype

Genotype
MGI:3817635

• Allelic Composition: Kit^W/Kit⁺; Tg(PGK1-KITLG*220)441Daw/0
• Genetic Background: involves: C3H/HeJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:32600 )

• 46% of mice show coat color similar to hemizygous transgenics or heterozygous Kit^W animals, while 29% show wild-type agouti coat coloring

• 25% of double mutants have a more severe deficiency in coat color pigmentation with large areas of hypopigmentation

hypopigmentation ( J:32600 )

hematopoietic system

decreased mast cell number ( J:32600 )

• numbers of connective tissue mast cells are greatly reduced relative to controls

immune system

decreased mast cell number ( J:32600 )

• numbers of connective tissue mast cells are greatly reduced relative to controls

integument

abnormal coat/hair pigmentation ( J:32600 )

• 46% of mice show coat color similar to hemizygous transgenics or heterozygous Kit^W animals, while 29% show wild-type agouti coat coloring

• 25% of double mutants have a more severe deficiency in coat color pigmentation with large areas of hypopigmentation