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Phenotypes Associated with This Genotype
Genotype
MGI:3817623
Allelic
Composition		 Chuktm1Yhu/Chuktm1Yhu
Egfrtm1Mag/Egfr+
Tg(KRT5-cre)5132Jlj/0
Genetic
Background		 involves: 129 * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chuktm1Yhu mutation (0 available); any Chuk mutation (53 available)
Egfrtm1Mag mutation (1 available); any Egfr mutation (88 available)
Tg(KRT5-cre)5132Jlj mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:141162 )
• most mice die but some survive
premature death ( J:141162 )
• most mice die but some survive

vision/eye
abnormal eye morphology ( J:141162 )
• mice exhibit eye defects

integument
abnormal coat/ hair morphology ( J:141162 )
• mice exhibit hair defects
thick epidermis ( J:141162 )
• slightly

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory