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Phenotypes Associated with This Genotype
Genotype
MGI:3815316
Allelic
Composition		 Hif1atm1Stom/Hif1atm1Stom
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (37 available)
Hif1atm1Stom mutation (0 available); any Hif1a mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased angiogenesis ( J:120332 )
• reduced number of microvessels form 2 weeks after transverse aortic constriction
abnormal heart size ( J:120332 )
• attenuated development of hypertrophy as a result of transverse aortic restriction
abnormal cardiovascular system physiology ( J:120332 )
• impaired cardiac function

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory