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Phenotypes Associated with This Genotype
Genotype
MGI:3814725
Allelic
Composition
Arhgdibtm1Miyo/Arhgdibtm1Miyo
Genetic
Background
involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgdibtm1Miyo mutation (0 available); any Arhgdib mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• a reduction occurs in the number of B cells found in the bone marrow of 18 week old mice is observed
• the number of T cells found in the bone marrow of 18 week old mice is reduced
• there is a 44% reduction in the number of circulating T cells found in adults

reproductive system
• mild spermatogenesis defects are noted in the testis of 16 week old mice but fertility is not affected

hematopoietic system
• a reduction occurs in the number of B cells found in the bone marrow of 18 week old mice is observed
• the number of T cells found in the bone marrow of 18 week old mice is reduced
• there is a 44% reduction in the number of circulating T cells found in adults


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory