Phenotypes for Ildr2 Lep MGI:3814225 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ildr2^Dbsm1-DBA/2J/Ildr2^Dbsm1-DBA/2J Lep^ob/Lep^ob
Genetic Background	B6.Cg-Ildr2^Dbsm1-DBA/2J Lep^ob

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ildr2^Dbsm1-DBA/2J mutation (0 available); any Ildr2 mutation (28 available)
Lep^ob mutation (5 available); any Lep mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

hyperglycemia ( J:138216 )

• increased fasting blood glucose levels in males up to 120 days of age

decreased circulating insulin level ( J:138216 )

• decreased blood insulin level in males

impaired glucose tolerance ( J:138216 )

• impaired glucose tolerance in males

endocrine/exocrine glands

decreased pancreatic beta cell mass ( J:138216 )

• decreased beta cell mass in males

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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