Phenotypes Associated with This Genotype

Genotype
MGI:3813521

• Allelic Composition: Rr275254^tm2.1Dhr/Rr275254^tm2.1Dhr
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal T cell receptor gamma chain V-J recombination ( J:75624 )

• Vgamma2 rearrangement is slightly reduced in the adult thymus

abnormal gamma-delta T cell differentiation ( J:75624 )

• there is less than 25% reduction in the number of precursor gammadelta T cells in the adult thymus that express Vgamma2

hematopoietic system

abnormal T cell receptor gamma chain V-J recombination ( J:75624 )

• Vgamma2 rearrangement is slightly reduced in the adult thymus

abnormal gamma-delta T cell differentiation ( J:75624 )

• there is less than 25% reduction in the number of precursor gammadelta T cells in the adult thymus that express Vgamma2