Phenotypes for Shh Sulf1 Sulf2 MGI:3812210 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Shh^tm1Chg/Shh⁺ Sulf1^Gt(XM190)Byg/Sulf1^Gt(XM190)Byg Sulf2^{Gt(PST111)Byg}/Sulf2^{Gt(PST111)Byg}
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shh^tm1Chg mutation (2 available); any Shh mutation (48 available)
Sulf1^Gt(XM190)Byg mutation (0 available); any Sulf1 mutation (113 available)
Sulf2^{Gt(PST111)Byg} mutation (1 available); any Sulf2 mutation (179 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal craniofacial morphology ( J:130163 )

• agnathic mice exhibit a narrow craniofacial region

absent mandible ( J:130163 )

• in 3 of 126 mice age E14.5 to E18.5

short mandible ( J:130163 )

• in 2 of 126 mice age E14.5 to E18.5

vision/eye

microphthalmia ( J:130163 )

• agnathic mice exhibit small or absent eyes

anophthalmia ( J:130163 )

• agnathic mice exhibit small or absent eyes

skeleton

absent mandible ( J:130163 )

• in 3 of 126 mice age E14.5 to E18.5

short mandible ( J:130163 )

• in 2 of 126 mice age E14.5 to E18.5

growth/size/body

absent mandible ( J:130163 )

• in 3 of 126 mice age E14.5 to E18.5

short mandible ( J:130163 )

• in 2 of 126 mice age E14.5 to E18.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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