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Phenotypes Associated with This Genotype
Genotype
MGI:3811825
Allelic
Composition		 Myctm2.1Atp/Myctm2.1Atp
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myctm2.1Atp mutation (0 available); any Myc mutation (42 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
absent fibroblast proliferation ( J:73369 )
• following treatment with a retroviral cre, mouse embryonic fibroblasts fail to proliferate in culture unlike wild-type cells

immune system
immune system phenotype ( J:73369 )
N
• despite cellular defects in T cell proliferation, activated T cells blast normally

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory