Phenotypes Associated with This Genotype

Genotype
MGI:3811359

• Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh; Foxc2^tm1Blh/Foxc2^tm1Blh
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryo phenotype ( J:91443 )

N • despite the lack of somites, proliferation and apoptosis rates of paraxial mesoderm are normal

abnormal mesonephros morphology ( J:91443 )

• at E9.5, mesonephric tissue is expanded and disorganized compared to in wild-type mice

abnormal somite development ( J:91443 )

• mice exhibit ectopic expression of intermediate mesoderm markers leading to increased lateralization of somites

absent somites ( J:91443 )

• mice lack somites