Phenotypes Associated with This Genotype

Genotype
MGI:3809748

• Allelic Composition: Cd19^tm1(cre)Cgn/Cd19⁺; Gt(ROSA)26Sor^{tm5(Map3k14)Rsky}/Gt(ROSA)26Sor^{tm5(Map3k14)Rsky}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

enlarged spleen ( J:139293 )

increased mature B cell number ( J:139293 )

• the number of mature peripheral B cells is increased resulting enlargement of the spleen and lymph nodes

• however, B cell proliferation is normal

increased marginal zone B cell number ( J:139293 )

enlarged lymph nodes ( J:139293 )

hematopoietic system

enlarged spleen ( J:139293 )

increased mature B cell number ( J:139293 )

• the number of mature peripheral B cells is increased resulting enlargement of the spleen and lymph nodes

• however, B cell proliferation is normal

increased marginal zone B cell number ( J:139293 )

growth/size/body

enlarged spleen ( J:139293 )