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Phenotypes Associated with This Genotype
Genotype
MGI:3806453
Allelic
Composition
Id2tm1Ago/Id2tm1Ago
Tg(TcraTcrb)1100Mjb/0
Genetic
Background
B6.Cg-Id2tm1Ago Tg(TcraTcrb)1100Mjb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Id2tm1Ago mutation (0 available); any Id2 mutation (17 available)
Tg(TcraTcrb)1100Mjb mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• adoptive transfer studies indicate that there is impaired accumulation of effector CD8+ T cells possibly because of an increase in apoptosis in these cells with surviving cells developing a central memory-like phenotype

hematopoietic system
• adoptive transfer studies indicate that there is impaired accumulation of effector CD8+ T cells possibly because of an increase in apoptosis in these cells with surviving cells developing a central memory-like phenotype


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory