Phenotypes for Gt(ROSA)26Sor Lhx3 Tg(tetO-SOD1,-luc)1Roos MGI:3806327 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1(tTA)Roos/? Lhx3^tm1(cre)Slp/Lhx3⁺ Tg(tetO-SOD1,-luc)1Roos/0
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(tTA)Roos mutation (3 available); any Gt(ROSA)26Sor mutation (1062 available)
Lhx3^tm1(cre)Slp mutation (0 available); any Lhx3 mutation (24 available)
Tg(tetO-SOD1,-luc)1Roos mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:138761 )

N	• mice show no significant differences from triple mutants carrying the G93A version of SOD1, in the rotarod test when tested at 300 days and later

growth/size/body

growth/size/body region phenotype ( J:138761 )

N	• body weight is similar to non-transgenic controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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