Lhx3^tm1(cre)Slp
Targeted Allele Detail

Summary

• Symbol: Lhx3^tm1(cre)Slp
• Name: LIM homeobox protein 3; targeted mutation 1, Samuel L Pfaff
• MGI ID: MGI:3513299
• Synonyms: Lhx3^Cre, Lhx3:CRE
• Gene: Lhx3 Location: Chr2:26090224-26098261 bp, - strand Genetic Position: Chr2, 18.44 cM, cytoband A2-C1
• Alliance: Lhx3^tm1(cre)Slp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:51420
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Lhx3^tm1(cre)Slp expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lhx3 (MGI:102673)

• Mutation details: An IRES_CRE_NEO cassette was cloned into the 3' untranslated region. Gene expression was not disrupted. (J:51420)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lhx3 (mouse) Summary of all recombinase alleles driven by Lhx3. Alliance mouse Lhx3 gene page

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lhx3 Mutation: 25 strains or lines available

References

• Original: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
• All: 12 reference(s)