Phenotypes Associated with This Genotype

Genotype
MGI:3805580

• Allelic Composition: Erbb2^{tm8.1(Erbb2)Mul}/Erbb2^{tm8.1(Erbb2)Mul}
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:89255 )

• no homozygous embryos are recovered after 12.5 dpc; embryos start to die by 11.5 dpc

cardiovascular system

abnormal myocardial trabeculae morphology ( J:89255 )

• reduction in trabeculation is observed at 12.5 dpc

muscle

abnormal myocardial trabeculae morphology ( J:89255 )

• reduction in trabeculation is observed at 12.5 dpc

nervous system

abnormal paravertebral ganglion morphology ( J:89255 )

• development is abnormal