About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3804426
Allelic
Composition		 Egr2tm2(cre)Pch/?
Gt(ROSA)26Sortm5(CAG-EGFP,-lacZ)Dym/?
Tg(Fev-flpe)1Dym/?
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr2tm2(cre)Pch mutation (2 available); any Egr2 mutation (32 available)
Gt(ROSA)26Sortm5(CAG-EGFP,-lacZ)Dym mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Tg(Fev-flpe)1Dym mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:136096 )
• alleles are used in intersectional and subtractive cell lineage fate mapping to visualize serotonin (5-HT) producing neurons and their precursors in the E12.5 embryonic hindbrain or mature brainstem
• rhombomere-3 (r3) rhombomere-5 (r5) derived 5-HT precursor cells are labeled by beta-gal while 5-HT precursors arising outside of r3 or r5 are labeled by eGFP

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory