Phenotypes Associated with This Genotype

Genotype
MGI:3804011

• Allelic Composition: Akt2^tm1.1Mbb/Akt2^tm1.1Mbb; Tg(MMTV-PyVT)634Mul/0
• Genetic Background: involves: 129 * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary adenocarcinoma incidence ( J:117336 )

• female virgin mice develop mammary tumors by 11 weeks of age which is significantly earlier than in mice carrying the transgene on a wild-type background

• parenchymal metastases of the tumors are found in the lung

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:117336 )

• female virgin mice develop mammary tumors by 11 weeks of age which is significantly earlier than in mice carrying the transgene on a wild-type background

• parenchymal metastases of the tumors are found in the lung

integument

increased mammary adenocarcinoma incidence ( J:117336 )

• female virgin mice develop mammary tumors by 11 weeks of age which is significantly earlier than in mice carrying the transgene on a wild-type background

• parenchymal metastases of the tumors are found in the lung