Phenotypes Associated with This Genotype

Genotype
MGI:3803970

• Allelic Composition: Akt1^tm1Pnt/Akt1^tm1Pnt; Akt3^tm1Mbb/Akt3^tm1Mbb; Tg(Lck-cre)1Cwi/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

thymus hypoplasia ( J:135903 )

• thymus cellularity is reduced by about 2.5 fold

decreased double-positive T cell number ( J:135903 )

• the percentage of double positive T cells in the thymus is reduced to 78.2% compared to 84.6% in wild-type mice

immune system

thymus hypoplasia ( J:135903 )

• thymus cellularity is reduced by about 2.5 fold

decreased double-positive T cell number ( J:135903 )

• the percentage of double positive T cells in the thymus is reduced to 78.2% compared to 84.6% in wild-type mice

endocrine/exocrine glands

thymus hypoplasia ( J:135903 )

• thymus cellularity is reduced by about 2.5 fold