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Phenotypes Associated with This Genotype
Genotype
MGI:3802653
Allelic
Composition
Del(2Hoxd11-Hoxd13)29Ddu/+
Hoxd13spdh/Hoxd13+
Genetic
Background
involves: 129S2/SvPas * C3HeB/FeJLe * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available); any Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available)
Hoxd13spdh mutation (1 available); any Hoxd13 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• less pronounced than in homozygotes of either component mutation
• variable syndactyly of digits III and IV, along with a supernumerary digit in between

reproductive system
• although males homozygous for either mutation are sterile, approximately 60% of these trans-heterozygotes are fertile

skeleton
• at 8 days of age the paws have some delay in the ossification process although ossification centers are observed


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory