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Phenotypes Associated with This Genotype
Genotype
MGI:3800908
Allelic
Composition
Apoc3tm1Unc/Apoc3tm1Unc
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoc3tm1Unc mutation (2 available); any Apoc3 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• total cholesterol levels are reduced in male mice but not female mice
• VLDL+LDL cholesterol levels are reduced by half in male but not female mice
• VLDL+LDL cholesterol levels are reduced by half in male but not female mice
• plasma triglycerides are reduced by 30% in both female and male mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory