Phenotypes Associated with This Genotype

Genotype
MGI:3800810

• Allelic Composition: Tg(APOA2)3Rub/?
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal lipid homeostasis ( J:92450 )

• a mean concentration of 34 mg/dl of human ApoA-II homodimer is found in the sera of mice without affecting the expression of endogenous apoliproteins

• HDL particle size has a bimodal distribution with two peaks at 8.0 and 9.6 nm compared to the single peak at 9.9 nm for non-transgenic controls

• the small size HDL particle contains the human ApoA-II