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Phenotypes Associated with This Genotype
Genotype
MGI:3799181
Allelic
Composition		 Rgsc263/Rgsc263+
Genetic
Background		 involves: C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgsc263 mutation (1 available); any Rgsc263 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating alkaline phosphatase level ( J:133634 )
• mice heterozygous for this mutation have low serum alkaline phosphatase (ALP) activity (203.6 IU/L vs. a control range of 343-732 IU/L)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory